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SUTENT is used to treat a rare cancer of the stomach, bowel, or esophagus called gastrointestinal stromal tumor (GIST) and when you have taken the medicine imatinib mesylate (Gleevec) and it did not stop the cancer from growing or you cannot take imatinib mesylate (Gleevec). Gleevec is a registered trademark of Novartis Pharmaceuticals Corporation.